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Ketogenesis. Ketogenesis is the process by which fatty acids are transformed into acetoacetate (AcAc) and 3-hydroxybutyrate (3HB) [1][2][3][4][5]. This process takes place in the liver in specialized organelles called mitochondria.
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Ketogenesis. Ketogenesis takes place in the mitochondria where fatty acid catabolism generates acetyl-CoA. Acetyl-CoA C-acetyltransferase (thiolase; EC2.3.1.9) joins two acetyl-CoA molecules, and hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase; EC4.1.3.5) adds another one.
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